Holy Basil (also known as Tulsi or Ocimum sanctum)

Summary (All / effects / data and information is essential benefits)
Holy Basil (also known as Tulsi or Ocimum sanctum) is a grass ayurvetic historically used to treat a variety of general medical conditions. Recently it has been shown to maintain the scientific value in the areas of protection of the liver and antioxidant activity in general in addition to being classified as an adaptogen (reducing the effects of stress on the body).

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It is also used as an aphrodisiac testosterone, although there was no direct evidence in humans for it. It was also shown that interfere with the ability to reproduce.



What You Should Know
Also known as

Ocimum sanctum, Tulsi Green, Holy Basil, Tulsi, Ocimum tenuiflorum


Not to be confused with

Thai Basil (a type of table)


Things to consider

Several studies using ethanol extract, suggesting that the active ingredients may be soluble in fat in nature
Probably one of the only enhance testosterone compounds (if it works) sperm is difficult, and perhaps related to the content of ursolic acid
Taking (the recommended dose, active and quantities, and other details)
500 mg of extract twice papers today seems to be recommended for Neurological and adaptogenic effects of holy basil, while the only evidence of other health effects, or the elevation of testosterone conducted in mice at doses of 100. of 200mg / kg and 500 mg / kg, respectively. This leads to a human dose is estimated:

1,100-2,200mg £ 150 for a person to public health and increase testosterone 5,500mg
1,500-2,900mg £ 200 for a person to public health and increase testosterone 7,300mg
1,800-3,600mg £ 250 for a person to public health and increase testosterone 9,100mg
This human dose calculated on the basis of animal research, and if the optimal safe dose for humans.
1. sources and authoring

Eleven. Use

Holy Basil, also known as Tulsi is Ayurvetic plant traditionally used for public health and long life. [1] Traditionally, the active ingredient is the oil extracted from the leaves, although traditionally used for a myriad of reasons and regonized more common to combat stress and pro-life characteristics. [2]

Herbal oils using his name Tenuiflorum, despite Ocimum sanctum is as synonymous; these terms and Holy Basil Tulsi and are interchangeable with regard to supplements.

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As an herbal supplement, holy basil has a few molecules. These include:

Ursolic acid [3]
Eugenol, [3] which tends to be seen as the active ingredient. [4]
Bioflavonols as APIGENIN and lutein [5]
Ocimumosides A and B [5]
Ocimarin [5]
Rosmarinic [6]


2. nerves

21. stress and anxiety

Some components of Ocimum sanctum, namelt ocimarin and ocimumosides A and B, it seems that the anti-stress activity when administered to mice at a dose of 40 mg / kg. [5]

In healthy people given Ocimum sanctum twice daily (500 mg each time after meals) within two months supplements appeared to reduce symptoms of generalized anxiety disorder and assessed by the community banks. [7]



3. Inflammation and Immunology
The court found in humans that after the consumption of 4 weeks of ethanol extract 300 mg Tulsi leaves, that the participants experienced an increase in some cytokines associated with the immune system; interferon p (IFN- r), interleukin-4 (IL-4) and helper T cells and NK cells . It has been observed [8] no effect on the cytotoxic T- cells or B- cells in this study. When the topics cells and chemicals pro-inflammatory LPS isolated (agglutinin vegetarian bloody) and immune cells were added Tulsi group more effective in mounting an immune adjustment through IFN-y cell response and Assistant T- and natural killer cells.

These immune secondary content of flavonoids effects of Tulsi may be. [9]



4. interact with hormones

4.1. Testosterone

The only effects seen holy basil in testosterone levels is the study of the Holy Basil rabbit eating 2 grams per day. [10] The previous study [11] [12] found reductions in sperm counts, reproductive potential, in parallel studies holy basil ursolic acid component. [13] [14]

One possible explanation is possible analog in androgen Holy Basil increases testosterone enough to suppress luteinizing and follicle stimulating hormones dramatically. [10]



5. Peripheral Systems

Bio X4. Liver

Holy Basil seems to be effective in the prevention of damage caused by toxins in the liver [15] [16] in body weight dose 100-200mg / kg. These protective effects, due to the occurrence of the alleged membrane components Holy Basil effect stability. [17]

Synergy has been observed in hepatoprotection when combined with milk thistle. [17]

Holy Basil, like other adaptogenic compounds, can reduce cadmium accumulates in the body [18] and protect the body from the toxicity of cadmium and developed [19] and reverse the accumulation. Ease [20] The proposed mechanism was also acting chelators antioxidant flavonol as metal or other oxidative stress enough cadmium for other chelators to work before damage can occur. [18]



6. Safety and Toxicity

6.1. Public

Toxicity extract has been reported from the Holy basil oil (containing 70 +/- 3% eugenol content [21]), was found to be 42.5 ml / kg of body weight. [22] [23] while the dry plant extract with natural content of eugenol has a LD50 between 4600-6400mg / kg of body weight in experimental animals. [8] [2] [24]