There is not much data on it yet.

Nucific Bio X4

Massularia acuminata is a stick of gum herbal aphrodisiac and medicine from the Yoruba in Nigeria.

It has been investigated in the past for effectiveness against gingivitis, but in recent times so as to deepen the characteristics of aphrodisiac her. Preliminary studies in mice suggest that this herb can increase testosterone and sexual activity.

There is not much data on it yet.



What You Should Know
Also known as

Baku Ijebu, Oren Ijebu


Things to consider

Active ingredients appear to be insoluble in water
Taking (the recommended dose, active and quantities, and other details)
According to the studies conducted on rats, a dose of 50 mg / kg and 1000 mg / kg appear to increase testosterone, while the highest dose associated with certain liver toxicity. For this reason, and based off estimated doses of 50 mg would / kg human:

550 mg of a person £ 150
700 mg of a person £ 200
900 mg of a person £ 250
Because there is no human evidence at this point in time, the above recommendations are nothing more than estimates.
1. Origin and components
Massularia acuminata (MA) is an aphrodisiac herb medicine Yoruba in Nigeria.

Plant contain a mixture of alkaloids anthraquinones, and saponins and phenolic compounds, flavonoids and tannins appear. [1] does not know the active ingredient.



2. influence on sexual activity, and testosterone
In many of the mice studies replicated has Massularia show acuminata (MA) to increase sexual standards in [1] do men increased testosterone, but did so on the approved level of sexual activity and less of Control (Viagra); can this increase be vicarious for increased sexual activity It is not the same complex.

Bio X4

Low doses are more effective than higher with the 50 mg / kg of body weight through increased sexual activity and testosterone more than 100 mg / kg and 200 mg / kg. [1] Although this relationship is inverted look in doses of 500 mg / kg and 1000 mg / kg of body weight, and levels of sexual hormone testosterone and begin to rise again. [2] [3] Group 1000 mg / kg peaked above the expected value, and was nearly twice the control. These studies have been conducted on healthy mice.

When 1000mg / kg in mice become human dose based on body surface [4] which translates to a dose of 160 mg / kg of body weight of Massularia accuminata. A lower dose 0.50 mg / kg, associated with 8 mg / kg of body weight and more rewarding.

There curve U-shaped in animals with 50 mg / kg and 1000 mg / kg of each to be effective, but have them to a lesser extent. Toxicity is associated with a dose of 250 mg / kg or more in animals, may be a dose of wisdom at this point in time


3. Safety and Toxicology
A study on mice to investigate on the face of the liver specifically indicators after eating Massularia soluble in water at 250 mg / kg, and 500 mg / kg, and 1000 mg / kg [5] observed a decrease in alkaline phosphatase activity (liver enzyme) and an increase alkaline serum levels phosphatase in each dose in the first initial oral dose, with similar effects at 250 mg / kg and a range of 500 mg / kg with a small group in the suppression of 1000 mg / kg. Similar increases were observed in the blood of activities aminotransferase serum aspartate aminotransferase alanine but increased in the liver (as opposed to alkaline phosphatase); have been observed increased bilirubin in the blood in each dose, and was seen no increases in a dose-dependent in albumin in the 500 mg / kg and 1000 mg / kg. [5]

The effects on the day on 21 for one direction of deterioration, but not statistically significant. [5]