Akarkara, Vajikaran Rasayana, Parietaria root, chamomile Spanish, pyrethrin

Nucific Bio X4

Pyrethrum is an herb Anacyclus improve the pro-fertility and virility, which is currently in the initial tests in rodents. And bioactive key in this plant are alkylamides (along the lines of Nkotaiat flowers acmella and appeal), and it seems that the initial evidence to confirm the traditional fertility claims and libido enhance its role as a "tonic brain" (apparently be against -amnesiac and the effects of anti-spasm).



What You Should Know
Also known as

Akarkara, Vajikaran Rasayana, Parietaria root, chamomile Spanish, pyrethrin


Things to consider

Do not share with pyrethrum insecticide pyrethrum, such as those made of Tanacetum cinerariifolium plant. The similarity between the two is only in name
Has been reported (anecdotally and through practice) that the application of pyrethrum cause skin redness and warmth with a little prick

Taking (the recommended dose, active and quantities, and other details)
Rat studies used a range of 50-150 mg / kg of body weight fever grass roots plant Anacyclus (DC) per day, with all the extracts tested (ethanol, petroleum ether and water) that appear to be effective. This results in the estimated human dose group:

550 to 1.600 mg per day per person, £ 150
700 to 2.200 mg per day per person, £ 200
900 to 2.700 mg per day per person, £ 250
These are only estimates of the effective range of root extract in humans, and there is currently no evidence in humans to base recommendations on.
Pyrethrum Anacyclus (family Astrassaa) is a plant and herb called Ayurveda Akarhara (dried root extract, also called pyrethrin [1]) or root Parietaria while being under the classification of Rasayana Vajikaran ability to other virility. Traditionally used fertility and sexual tonic herb, as well as brain tonic to cure paralysis, hemiplegia, headache (headache), epilepsy and rheumatism. [2] It is believed also to 'cleanse' the body of toxins by stimulating blood flow to the brain and face, and causes increased secretion of saliva and mucus flow. [3]

Elsewhere, as it is known Akarkarabh or akallaka (North Africa), where he grew up just before being introduced to India. [4] It is also known as the Spanish chamomile scheduled to find visually similar to chamomile plant.

Pyrethrum is an herb traditionally used for vitality and virility, with additional benefits in cognition

1.2. Installation

Pyrethrum Anaclcus tends to contain (root extract unless otherwise stated):

13 alkylamides based mainly isobutylamide outside [1] which includes the N-isobutyldienediynamide (pellitorine or pyréthrine) [5] [6] and Anacylin [4] as alkylamides Home
Hydrocarolin [4]
Cereals [4]
Sesamin [4]
Sugars in hot water passage of the solution [3]


Known biologically active alkylamides Root Extract speak, although the composition of this plant is not well known at this point in time


2. nerves

21. Epilepsy

200-600mg / kg Anacyclus ethanol extract pyrethrum 30 minutes before the Nuba caused by stun seems to exert protective effects at the lowest dose being the most effective (71.37% recovery), but at least 25 mg Energy / kg phenytoin. [4] In addition, water-alcoholic extract 50-500 mg / kg orally showed protective effects when ingested by pentilentetrazol- highest seizure caused by (Protection of 50-100%) and dose (100 to 1.000 showed mg / kg) induced protection seiure (16,7 Up to 50%) Electric. [2]

It is reduced by changes in vital signs oxidation (enzymes and TBARS) and acetylcholine noted seizures by treatment pyrethrum. [2]

It seems pyrethrum Anacyclus that have anti-convulsant properties seen after oral ingestion in rats

Bio X4. Memory and cognition

In mice with memory impairment caused by scopolamine, / kg and supplements to extract ethanol from pyrethrum in 50-200mg effective in preserving the memory acquisition and retention with 100-200mg / kg dose being compared in power for drug reference piracetam (200 mg / kg) . [7] It seems pyrethrum also to strengthen the social memory with similar efficacy to piracetam. [7] also it observed adverse effects of memory loss in mice with induced convulsions (usually reduced cognitive performance) due to fighting properties spasm pyrethrum. [2]

This herb seems to have a fighting properties have respected the memory, although the pro-cognitive properties of their own (for use tonic mind) have not been evaluated as if he does not exceed the potential drug reference


3. Inflammation and Immunology

3.1. Macrophages

Pyrethrum was polysaccharide Anacyclus 25-50 mg / kg (IP) injection is able to increase the connective phagocytocic rate in the range of 50-115% with 10 mg / kg and 100 mg / kg is not effective, the highest authority and Handal still under Alpinia galanga. [3] When tested in vivo, and was 50-100mg / kg for the extraction of oil ether able to maintain the presence of phagocytosis cyclophosphamide. [8]

Pyrethrum Anacyclus seems to increase the phagocytosis of macrophages and avoid immunosuppression

3.2. Lymphocytes

The number of immune cells in the spleen cells appears to increase with 25-50 mg / kg injection polysaccharide pyrethrum, which refers to the mitogenic effect. [3]

It seems to have mitogenic effects, despite the failure to reach a population of cells that are stimulated


4. interact with hormones

4.1. Testosterone

Supplements anacyclus root extract pyrethrum ethanol (50-150 mg / kg) more than 28 days in mice indicated a dose-dependent increases in testosterone and Almhloten to about twice baseline (do not give values ​​to be exact). [1] However, it anacyclyus works by stimulating the hypothalamus, and alkylaimde class of molecules (also seen in Nkotaiat flowers acmella) It is known that to work in this way. [9]

You can increase testosterone in normal mice odds with improving fertility effects


5. sexual interactions

5.1. concupiscence

A water extract of pyrethrum anacyclus in 50-100mg / kg for 28 days and it seems that has improved properties because of sexual desire to improve penile erection index (202%), and the increasing frequency of access (an increase of 196 266% and 173-384%, respectively), the underlying collection and intervention period (82-90% and 63-76% of the base, respectively). Remain [10] all the parameters dose and time dependent (100 mg / kg than 50 mg / kg and 28 days 15 days beating) and continued until 15 days after supplementation [10] and the values ​​of similar has been observed elsewhere in the petroleum ether extract. [Eleven]

It seems that improve libido relatively strong properties that will last for several weeks after stopping supplement


6. interaction with organs of the body

Bio X4. Testicles

Oral ingestion of 50-150 mg / kg of ethanol extract of the roots of a plant grass fever Anacyclus more than 28 days to male rats it seems to cause an increase in testicular weight (2.6 up to 12.3%), and in particular, in the epididymis (8.6 up to 26.1%) and seminal vesicles (4.3 to 9.8%). [1] were similar to inject large doses of 0.5 mg / kg of testosterone was not associated with an abnormal histological signs [1] and similar changes have seen with aqueous extract lyophilized [10] and extraction of oil ethereal. [Eleven]

As for the previous doses seminal fluid was observed to increase sperm motility, safety, and fructose, and counting. [1]

There seems to be an increase in testicular weight and sperm parameters suggest increase fertility in male rats

6.2. Prostate

In mice, oral ingestion of 50-150 mg / kg of ethanol extract of the roots of a plant grass fever Anacyclus more than 28 days show an increase prostate weight (7.5 up to 21.5%) associated with the activity androgenic. [1] This has been observed in any other place to get a similar degree, but a little less. [10] [11]

There seems to be an increase in prostate weight associated with this herb, perhaps related activities masculinity


7. Safety and Toxicology

7.1. Public

300-2,000mg / kg of ethanol root extract to kill any rats failed completely within 24 hours of observation [4] and the other study, noting that '50 mg / kg and 100 mg / kg was 20.1 and 10/01 LD50 indicate that this value is set at 1000 mg / kg for long-term use (oil root) extract. [8] However, a longer study (90 days) using the 1000 mg / kg of ethanol extract in mice failed to find any evidence of toxicity. [12]